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So, like CBD, grapefruit juice can boost levels of other medications in your blood. Experts share how cannabidiol can impact anxiety medication, blood thinners and even pain relievers.

Statins are a classification of drugs designed to lower cholesterol and protect against heart attack and stroke. Common side effects of statins are muscle soreness, blood sugar increase, headaches, and nausea. No research has explicitly documented interactions between Xanax and CBD. Patients taking Xanax who are interested in CBD should speak to their healthcare providers for more information. The type, quality, and purity of CBD administered all affect how it interacts with your body and medication.

One of the biggest concerns we’ve come across are CBD drug interactions and if CBD is safe to take with other medications. The second category of drugs is those which require using some caution when taking them with CBD. Prescriptions may fall into this class because what is hemp oil they either increase or decrease how quickly your liver enzymes are able to break down the drugs, thus either reducing or intensifying their effects. Other users find that the cannabinoids within CBD products help ease mental health conditions. The information in this article is based on current research and should not be construed as medical advice.

The timing of when you take CBD and any other prescription drug also factors into how the two may interact in your body. And of course, every individual responds to medications differently, depending on genetics, age, weight, and other factors. The study postulated that while the blockage could allow patients to take lower doses of their prescriptions, it could also cause a toxic buildup of chemicals in the body. Since this study’s publication, several scientific and medical journals have published evidence of the grapefruit-like effects of CBD in humans. Many doctors urge individuals using CBD to be cautious about mixing it with other prescriptions and to consult healthcare providers about possible interactions.

CBD can reduce or increase the effects of certain prescribed medications by interacting with receptors throughout the body’s Endocannabinoid System (ECS) and by inhibiting the activity of cytochrome P450. Due to the nature of chemical compounds, virtually every substance, including CBD, will interact with other substances. For instance, labels on a variety of prescription drugs will advise you to avoid grapefruit when taking the medication because it can significantly affect how the body metabolizes the drug. Considering the ambiguity of what’s really in some of these prescribed medications and how they work with the body compared to how Cannabidiol (CBD) works with the body, this is indeed a very concerning subject.

Please be advised that this list does not include all drugs that can interact with grapefruit or CBD, and it is highly recommended that you consult with your physician before taking Cannabidiol (CBD). Cytochrome P450 is a group of liver enzymes that are responsible for breaking down drugs and toxins that enter the body. By inhibiting the activity of this enzyme, CBD can temporarily deactivate its activity, which can alter how other compounds are metabolized.

There are also other medications known as “prodrugs” that first need to be metabolized into its therapeutic compounds as opposed to being a therapeutic compound in and of itself (like most medications). In other words, the inactive compound is ingested, and once in the body, it is processed into its active compound. When the CYP system is affected in this way by CBD, it both changes and the way in which certain other drugs are metabolized as well as prevent a lot of the drug to be metabolized.

Please speak to your doctor or healthcare provider if you have questions regarding your medication and CBD use. Clobazam, used to treat epileptic seizures, is another type of drug that may not be advisable to take in conjunction with CBD. However, Epidiolex is an FDA-approved, CBD-based drug that physicians may prescribe to treat epilepsy.

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